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Pfizer to Acquire Trillium Therapeutics for $2.3B

Strengthens oncology portfolio with addition of next-generation, investigational immuno-therapeutics for hematological malignancies.

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Pfizer has strengthened its oncology pipeline with a deal to acquire the clinical stage immuno-oncology company Trillium Therapeutics for $2.26 billion.   Trillium’s portfolio includes biologics that are designed to enhance the ability of patients’ innate immune system to detect and destroy cancer cells. Its two lead molecules, TTI-622 and TTI-621, block the signal-regulatory protein α (SIRPα)–CD47 axis, which is emerging as a key immune checkpoint in hematological malignancies. TTI-622 and TTI-...

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